Best Diaper Rash Creams

reviewed mark Medically Reviewed by Jessica Wu, M.D.
Updated: July 22, 2021
Best Diaper Rash Creams

At some point in your parenting journey, you’ll open up your little one’s diaper and find a red, sore-looking bottom.

Diaper rash is a common skin irritation that’s typically triggered by a combination of moisture, air, friction from diapers and irritants caused by poop, pee or even the ingredients in diapers or bath products. Sometimes yeast (which loves moisture) is involved, particularly with severe or recurring rashes.

But no matter what the cause, you’re going to want to help relieve baby’s symptoms — stat. The good news? Diaper rash cream can help.

Why you need a baby diaper rash cream

While getting to the root cause of diaper rash is crucial for getting rid of the red, warm, bumpy rash, using a diaper rash cream can help provide relief as your baby’s sensitive skin heals and prevent future flare-ups. How? “Diaper rash comes from moisture to the skin, which allows yeast and bacteria to flourish,” says Michele Green, M.D., a board-certified dermatologist in New York City. “By creating an occlusive layer, and minimizing the moisture, these organisms won’t grow.”

Types of diaper rash treatments

Faced with an aisle lined with options, you may wonder how to even begin to choose a quality diaper rash cream — especially when those ingredient lists are so lengthy.

Before stressing over each individual ingredient, you should know that there are two main types of diaper rash cream:

  • Petroleum-based products, like classic petroleum jelly and Aquaphor
  • Zinc-oxide based products, including Desitin or Balmex

What to consider when choosing the best diaper rash cream

First, consider the type of rash your baby has. If the rash is mild, a petroleum-based product may be sufficient. But if your baby has a moderate to severe rash, zinc oxide-based products will provide a bit more protection from further irritation. Also know that thicker creams and pastes are best for soothing existing or severe rashes, while ointments are ideal for preventing diaper rash from occurring in the first place. 

Now, take a look at the lengthier list of ingredients: Look for ingredients like zinc oxide and lanolin, says Green. “Anti-fungal creams, A+D ointment, Balmex, Triple Paste and Butt Paste are all good choices to treat diaper rash.”

Conversely, you should avoid products containing boric acid, camphor, phenol, baking soda, salicylates or diphenhydramine, because they can be toxic to babies, says Green. “You also want to minimize the use of hydrocortisone cream, as it can thin the skin.” Products with heavy fragrance can cause even more irritation, which is why it's not recommended by the American Academy of Pediatrics (AAP).

It may also help to experiment and try different creams to see which works best for your baby’s bum and type of diaper rash.

To apply diaper rash cream correctly, dry the skin well before applying and wash the area with a gentle cleanser free from perfumes, says Green. And don’t forget to change baby often. Though you don’t have to apply cream with each change, a zinc oxide cream can work as a preventative measure. (Anti-fungal creams used to treat active diaper rash should only be used two or three times a day, says Green.)

If the rash persists, make sure you’re applying it correctly before jumping from product to product, though. Baby’s bottom should be completely dry before you slather on your diaper cream of choice gently and liberally all over the area. You don’t need to — and shouldn’t — wipe the cream off between changes, but make sure the area has dried a little before putting a new diaper on your baby. (Remember: moisture breeds bacteria.) After wiping, you can fan the area or wait a minute or two before closing the diaper and getting baby dressed.

How we made our picks for the best diaper rash cream

We chose the following products based on the AAP recommendations for diaper rash creams to ensure all products on the list are as safe and effective as possible. Among the items that fit that criteria, we selected top-rated and highly-reviewed products — both petroleum-based and zinc oxide-based — that parents in our community swear by.

Frequently Asked Questions

What is the best cream for diaper rash?

First, consider the type of rash your baby has. If the rash is mild, a petroleum-based product may be sufficient. But if your baby has a moderate to severe rash, zinc oxide-based products will provide a bit more protection from further irritation.

What heals diaper rash fastest?

To heal a diaper rash quickly, use diaper rash cream. Moisture is your enemy, so make sure to dry your baby's skin well at every diaper change (before applying cream). And don’t forget to change baby often.

What's better for diaper rash — ointment or cream?

Thicker creams and pastes are best for soothing existing or severe rashes, while ointments are ideal for preventing diaper rash from occurring in the first place.

What's good for severe diaper rash?

Thicker creams and pastes are best for soothing existing or severe rashes.

Why Trust Us?

Best Diaper Rash Cream

Aquaphor Baby Diaper Rash Cream & Healing Ointment

Best Diaper Rash Creams - Aquaphor Baby Skin Care Set
Buying Options:
Amazon
Amazon
$25
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Walmart
$14
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buybuyBaby
$16
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Bed Bath & Beyond
$16
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Pros: Creates an excellent moisture barrier, easier to wash off fingers, great value
Cons: Not as healing as other formulas

Why We
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Why We Love It

This diaper rash cream, sold with Aquaphor's Baby Healing Ointment (made to prevent diaper rashes), is excellent for creating a moisture barrier to protect baby’s skin from loose stools.

Plus, this system isn't just great for preventing or healing diaper rash on your baby — the highly versatile healing ointment is sure to become a household favorite long beyond the baby years, since adults can also use it to heal dry skin and chapped lips, repair cracked cuticles and tame flyaways.

Size: 3.5 ounces (diaper rash cream); 14 ounces (healing ointment)

Community Reviews

"Aquaphor diaper cream. We’ve been using it since my son was a baby in 2016 and using it for this baby as well. Works great!"

- MKJ20191

"Aquaphor has been working great so far, as soon as I start to see redness I apply and it goes away within the next few diaper changes."

- tmatusik20

Most Versatile Diaper Rash Cream

Grandma El's Diaper Rash Ointment

Best Diaper Rash Creams -Grandma El's Diaper Rash Ointment
Buying Options:
Amazon
Amazon
$13
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Registry List:
Pros: Cloth diaper-safe, a little goes a long way, smells good
Cons: Expensive, slightly sticky

Why We
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Why We Love It

Made in the U.S., this diaper rash cream boasts lanolin, vitamin E and amber petrolatum (a protective ingredient). It's also cloth diaper-safe and can be used on eczema, heat rash, minor burns and cradle cap, too. It comes in a 3.75-ounce jar, as well as a 2-ounce tube.

Size: 3.75 ounces

Community Reviews

"This stuff is amazing. Baby can have the angriest little red bum ever, slather this on, and next change everything is right as rain. I have also used it on chafed skin, dry cracked knuckles, and blisters, It's just amazing. Oh, and it's cloth safe too! Seriously, I can't say enough good things about this stuff."

Best Diaper Rash Cream for Sensitive Skin

Babo Botanicals Soothing Diaper Cream

Best Diaper Rash Creams - Babo Botanicals Soothing Diaper Cream
Buying Options:
Amazon
Amazon
$12
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Registry List:
Pros: Natural ingredients, a little goes a long way
Cons: Strong smell, temperature sensitive

Why We
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Why We Love It

With colloidal oatmeal and organic calendula flower extract, this zinc oxide-based diaper rash cream soothes diaper rash without irritating even the most sensitive skin. It also moisturizes, thanks to shea butter. Moms of babies with allergies will also find comfort in the fact that this formula is gluten-, soy-, dairy-, peanut-, almond- and walnut-free. Still, it’s highly effective, thanks to a 25 percent non-nano zinc oxide formula.

Size: 3 ounces

Community Reviews

“This is one of my favorite diaper rash creams! And trust me, I’ve tried them all.”

Best Hypoallergenic Diaper Rash Cream

Boudreaux's Butt Paste for Sensitive Skin

Best Diaper Rash Creams - Boudreaux Butt Paste
Buying Options:
Amazon
Amazon
$8
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Walmart
$8
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buybuyBaby
$11
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$11
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Pros: Easy to spread, hypoallergenic, doesn’t contain fragrances
Cons: Hard to wipe off of skin, lower concentration of zinc oxide

Why We
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Why We Love It

Boudreaux is known for their incredibly popular original butt paste, and now they have this sensitive-skin option, which is made with just five ingredients: zinc oxide (the primary one), mineral oil, castor seed oil, petrolatum and paraffin. Even better, it’s free of fragrances, dyes, parabens and preservatives. But just because it’s gentle, doesn’t mean it’s ineffective. This easy-to-spread cream has all the same benefits of the beloved original formula and is guaranteed to help nourish baby’s bottom, while adding an emollient layer of protection from wetness.

Size: 4 ounces

Community Reviews

"I highly recommend this paste! A little goes a long way and it helps clear it up quickly! It’s all we use for my daughter."

- nkmitchell3

"My little had a rash for weeks and was on a prescription that did nothing. We used this and seriously it was gone in two days and never came back."

- skokiegreen

Best Affordable Diaper Rash Cream

Desitin Rapid Relief Diaper Rash Remedy

Best Diaper Rash Cream - Desitin Rapid Relief Diaper Rash Remedy
Buying Options:
Amazon
Amazon
$13
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buybuyBaby
$14
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Bed Bath & Beyond
$14
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Walmart
$13
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Pros: Hypoallergenic, affordable, comes in multiple sizes
Cons: Lower concentration of zinc oxide

Why We
Love it
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Why We Love It

This healing diaper rash cream is gentle enough to be used daily as a preventative treatment (it contains no parabens, phthalates, fragrances or dyes).  Just know that at a concentration of 13 percent zinc oxide, this cream contains less than some of the other brands on the list, so it may not be as suitable for severe rashes. That said, it’s an affordable choice for those on a budget — and will provide ample protection for mild to moderate cases. It comes in a 16-ounce tub, so it'll likely last for quite a while, too. But don’t worry: If this cream secures a spot as your favorite, it comes in more portable sizes — like a 4-ounce tube.

Size: 16 ounces

Community Reviews

"Desitin is miracle cream, in my opinion!”

- Superexcitedmommy2

"We have tried everything and found Desitin works the best!! We see relief after one use!"

- hopealexis

“I will forever swear by Desitin. The stuff is magical.”

- Silmarwen

Best Fast-Acting Diaper Rash Cream

Triple Paste Medicated Ointment

Best Diaper Rash Creams - Triple Paste Medicated Ointment
Buying Options:
Amazon
Amazon
$30
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Registry List:
Pros: Expensive, treats a wide range of skin conditions, hypoallergenic
Cons: Lower concentration of zinc oxide

Why We
Love it
Community
Reviews
Why We Love It

If nothing else works for your baby’s stubborn diaper rash, give this fragrance-free and hypoallergenic formula a try. Though it’s a little pricier and only contains 12.8 percent zinc oxide, parents swear it gets rid of stubborn rashes fast. And if their word for it isn’t enough for you, you can feel comforted by the fact that if it doesn’t work for your baby, the company will refund your money, no questions asked.  

Size: 16 ounces

Community Reviews

"Triple paste- it has corn starch in it! It’s the only thing that has worked for us!"

- Scrubs8

Most Mom-Friendly Diaper Rash Cream

Balmex Complete Protection Zinc Oxide Diaper Rash Cream

Best Diaper Rash Creams - Balmex Complete Protection Zinc Oxide Diaper Rash Cream
Buying Options:
Amazon
Amazon
$14
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Registry List:
Pros: Washes off easily, proven to reduce symptoms and rash itself, multiple sizes
Cons: Temperature sensitive, harsh smell

Why We
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Why We Love It

This diaper rash cream easily washes off your hands — which is important when you’re doing up to 10 (or more) diaper changes in a day. And when you have a crying baby on your hands, trust us: You don’t want to labor over the sink trying to wash off a stuck-on cream.

Despite the ease at which it comes off of your own hands, the creamy formula protects baby’s bottom from chaffing and wetness, but also soothes her delicate skin. It’s also clinically-proven to actively reduce redness in three hours.

It comes in a 16-ounce jar, and smaller tubes are also available, so you can stock both your home and your diaper bag with the most convenient size.

Size: 16 ounces

Community Reviews

“Balmex is the BEST diaper cream. No petroleum, no icky smell - just lanolin and zinc. Keeps baby comfortable and rash-free. Also great for soothing the mouth area and chin for babies who drool, or for a very protective winter cheek moisturizer.”

Best Organic Diaper Rash Cream

Earth Mama Organic Diaper Balm

Best Diaper Rash Creams - Earth Mama Organic Diaper Balm
Buying Options:
Target
Target
$13
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Pros: Safe for cloth diapers, certified organic and non-GMO, plant-based ingredients
Cons: Strong smell, expensive

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Why We Love It

Created by a mom, this USDA-certified, organic diaper rash cream contains plant-based ingredients — including olive oil, beeswax and shea butter — to gently nourish baby’s skin while fighting diaper rash. That certification alone is enough to sell some parents, since it’s not a label you’ll find on a lot of other diaper rash creams.

The formula is safe for use with cloth diapers — a no-no with most mineral oil-based diaper creams — and can also be used on minor cuts and scrapes. It's sold in a 2-ounce tube, and sets are available.

Size: 2 ounces

Community Reviews

"This is the best balm I have used ! I bought one for my niece as well who had a rash that kept getting worse and it helped clear it up in a day ! It’s not sticky and goes on clear and glossy reminds me of coconut oil texture, Highly recommend !"

Best Classic Diaper Rash Cream

A&D Original Diaper Ointment

Best Diaper Rash Creams - A&D Original Diaper Ointment
Buying Options:
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Rite Aid
$4
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Pros: Easy to spread, rinses off hands easily
Cons: Unpleasant smell

Why We
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Why We Love It

From the makers of Bayer, this diaper ointment has been a trusted brand for generations of moms. It’s what your parents used, and it’s just as effective today. In addition to petrolatum, it contains vitamins A and D (hence the name) and lanolin to soothe and protect baby’s bum. It’s a fantastic staple to have in the house, too — use it to help with cracked lips or swipe it onto minor scrapes and cuts. It’s affordable and widely available in a wide range of sizes, including this convenient 4-ounce tube.

Size: 4 ounce tube

Community Reviews

"A and D hands down. My baby has only had a diaper rash once for a couple hours when we forgot to put it on after a couple changes. It doesn’t smell the best but it IS THE BEST"

- juliablanchette

Best Subscription Diaper Rash Cream

Honest Diaper Rash Cream

Best Diaper Rash Creams - Honest Diaper Rash Cream
Buying Options:
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Honest Co.
$10
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Pros: Can set up recurring deliveries, hypoallergenic
Cons: Expensive

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Why We Love It

If you’re already getting your diapers delivered from The Honest Company, just add this cream onto your next shipment. The zinc-oxide based cream contains soothing jojoba and coconut oils and is free of parabens, synthetic fragrances, phthalates, silicones, lanolin and more. 

Size: 2.5 ounces

Community Reviews

“Try Honest, started using it and rashes never came back”

- Starrmom

“The diaper rash cream is INCREDIBLE!!!!!! I'm talking it's a diaper rash CURE!!! Trust me.”

- MamaRobert

Best Plant-Based Diaper Rash Cream

Evereden Soothing Diaper Rash Cream

Best Diaper Rash Creams - Evereden Diaper Cream
Buying Options:
Amazon
Amazon
$10
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Registry List:
Pros: Spreads easily, doesn’t stick to hands, plant-based ingredients
Cons: Expensive

Why We
Love it
Community
Reviews
Why We Love It

There’s a lot to love about this plant-based diaper rash cream. For starters, it’s formulated with good-for-baby ingredients, like soothing kakadu plum, sunflower seed and coconut oils. We love the consistency of the formula, too. It’s not too thick, not too runny — and it doesn’t stick to your hands the way some others do. What’s more, there’s no harsh smell. The cream has a fairly neutral scent that just about anyone can get on board with.

Not to mention, the product has insanely cute branding that makes you feel hip just for having it in your arsenal of baby gear. One thing’s for sure: After trying this cream, you’re bound to want to explore the company’s other products, which includes one of the most delicious-smelling baby shampoos you’ve ever tried.

Size: 3 ounces

Community Reviews

“Great diaper rash cream. Works well, great barrier for babes who need that really solid barrier cream. No fragrance added or nasty additives. I haven't had any big issues with separation of the product. Easy to get a good amount out of the tube and a little goes a long way. I'm happy with it!”