Best Bottles for Preemie Babies

reviewed mark Medically Reviewed by Jennifer Wu, M.D., F.A.C.O.G.
Updated: March 30, 2023
best preemie bottles

Finding the right bottle for your little one can already feel overwhelming, but preemies often have unique feeding challenges compared to full-term babies that make finding preemie bottles and nipples extra tricky for parents.

Babies born early (meaning if they arrive before 37 weeks) may have trouble sucking and swallowing milk, and their intestines often need more time to develop. For this reason, preemies in the NICU are sometimes initially fed with an IV or a tube that goes through their nose or mouth.

Once preemies are able to be breastfed or bottle-fed, they may have a harder time latching on or need a slower flow to avoid overloading their smaller stomachs. This is when preemie bottles can come in handy, as they are often specifically designed for the unique feeding needs of preterm babies. You can fill them with your own pumped breastmilk or with formula, depending on how you’re choosing to feed your baby.

It’s difficult to say when your little one will be ready to transition to a more traditional bottle. But, in general, your baby will let you know when it’s time. “Follow their cues,” says Anjuli Gans, M.D., attending physician at CHOP Karabots Pediatric Care Center and clinical assistant professor of pediatrics at the University of Pennsylvania Perelman School of Medicine. “If they are still hungry and showing feeding cues after finishing their bottle, you can advance to larger volumes as they tolerate it,” she says. “They might be ready for a larger bottle.” 

To get your baby started out, it’s important to choose a preemie bottle. Here’s what you need to know about picking the right bottle, plus some options to consider. 

How we chose the best bottles for preemies

  • We consulted two pediatricians — Dr. Gans and Daniel Ganjian, M.D. — for their input on the unique feeding needs of preterm babies and the most important qualities to look for in preemie bottles. Per their advice, as well as guidance from the American Academy of Pediatrics (AAP) on bottle feeding babies, all of the bottles on our list: 
    • Are sized between 2 and 5 ounces
    • Come with slow-flow nipples or can easily use slow-flow nipples, which are ideal for feeding preemies
    • Have nipples in preemie, 0+ or 0-6 sizing
    • Are BPA-free
  • We considered feedback and reviews from the What to Expect community to ensure we choose options that real parents love. 

Preemie bottle features to consider

There are a few things to keep in mind while shopping for a preemie bottle. Those include:

  • Size: Preemies generally take smaller amounts of food in one feeding, says Dr. Ganjian, so you don’t need a massive bottle for your baby. Some companies offer smaller quantity bottles so you're not feeding a tiny baby with a giant bottle.
  • Shape. The right bottle shape for your baby depends on whether she has certain health conditions. For example, baby may do better with a narrow nipple or shallow nipple if she has a unique oral anatomy like a high palate or tongue tie, Dr. Gans says. “Other brands have wider-based nipples that may be more comfortable to babies who are getting used to breastfeeding,” Dr. Gans says. Ultimately, it’s a good idea to talk to your doctor to see what they recommend. 
  • Nipple flow. Many popular bottles have preemie-friendly nipples with a slower flow to help with feeding. 
  • Anti-colic options. Bottles that can effectively reduce air intake and provide a slow flow are often preferred among parents of preemies who have just come home from the hospital. These can help reduce colic, Dr. Ganjian says. 
  • Safety. “Make sure that the bottles are easy to clean and sterilize,” Dr. Gans says. “Premature babies may be more prone to serious infection, so making sure that their bottles are regularly and easily sterilized is crucial.” 
  • Baby preference. Many WTE parents caution not to invest in a huge set of bottles until you know what your baby likes — sometimes babies are really particular about one bottle. You might want to try one or two of a few kinds and experiment to see what works best for your little one.

Do premature babies need different bottles?

Every premature baby is different, and has unique needs that will dictate the best bottles for them. Some may require special preemie bottles, while others will do just fine with regular bottles. You may want to consult your pediatrician and take into account the previously mentioned factors, like baby’s oral anatomy and liquid intake, before deciding. 

How do you feed a preemie with a bottle?

There are a few different methods you can try. One is paced bottle-feeding, which focuses on slowing down the flow of milk into the nipple, allowing baby to eat slowly and take breaks, Dr. Gans says. “This allows the baby to pace themselves and to learn the mechanics of sucking and swallowing while helping with conditions like reflux,” she explains. 

Another method Dr. Gans recommends is combination feeding, which is when you breastfeed and bottle feed your child. If you go this route, she suggests doing paced bottle feeding when you use a bottle. You should also wait until your neonatologist or pediatrician has given their approval to ensure that your preemie baby is ready and healthy enough to start trying breastfeeding. [5] And don’t be shy about asking the NICU nurses or tapping a lactation consultant to help you with technique. 

Here, some of the top bottle options on the market for babies who arrived early. 

Why Trust Us?

Best Preemie Bottle Overall

Dr. Brown's Natural Flow Anti-Colic Baby Bottle with Preemie Flow Nipple

dr browns natural flow preemie bottles
Buying Options:
Amazon
Amazon
$23 for 4
See Now buybuyBaby
buybuyBaby
$12 for 2
See Now Target
Target
$11 for 2
See Now Walmart
Walmart
$16 for 2
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Registry List:
Pros: Works well with most babies, parents say it helps with gas and colic
Cons: Some parents say the bottles leak

Why We
Love it
Community
Reviews
Why We Love It

There’s a reason this bottle has had a near cult-like following since it was launched in 1996. It simply works well for newborns, and preemies are no exception. “I love the Dr Browns products! We were gifted two bottles at our baby shower and went to buy two more and the sanitizer when we saw how easy our LO took to them, no nipple confusion and way less burping!” raves one What to Expect Community mom

This set of two-ounce bottles — ideal for feeding little preemies without overloading them — has super slow-flow nipples that will work with your baby through the preemie stage. The internal vent system, a standard on the brand’s bottles, is also designed to cut down on extra air in the bottle to help reduce colic and gas. Many members of the What to Expect community say that this is the only bottle their baby will take.

Material: BPA-free plastic

Capacity: 2 ounces

Bottles per Package: 2 or 4

Community Reviews

“They hold 2 ounces and the nipple is preemie slow. My son is still having some trouble with feedings but he has done best with these bottles.” 

- veronicamcneal

“My LO had apnea spells and gerd (reflux), NICU sent us home on Dr. Brown’s. He had no problem transitioning from breast to bottle in the same sitting.” 

- Tramsey

Best Preemie Bottle for Easier Latching

Philips Avent Natural Baby Bottles

phillips avent natural response baby bottle
Buying Options:
Amazon
Amazon
$30 for 4
See Now buybuyBaby
buybuyBaby
$24 for 3
See Now Target
Target
$23 for 3
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Registry List:
Pros: Doesn't leak, easy to clean
Cons: Discontinued their preemie-specific nipple

Why We
Love it
Community
Reviews
Why We Love It

Philips Avent is another bottle you’re likely to see everywhere, especially among preemie families. The nipple is soft and flexible, making it easier for baby to latch, and it has built-in air vents to help reduce the amount of bubbles baby takes in during feedings. These 4-ounce bottles have the option of swapping in the brand’s anti-colic nipple, which has an extra-slow flow perfect for preemies. The wide neck of the bottle and minimal parts also makes it super easy to clean and sterilize.

Material: BPA-free plastic

Capacity: 4, 9 or 11 ounces

Bottles per Package: 3 or 4

Community Reviews

“We also use the Avent Slow flow bottle depending on how gassy she is that day…she seems to favor the Avent due to the shape.”

- LaylaMarlene

Best Preemie Bottle for Breastfed Babies

National Baby Company Comotomo Baby Bottles

comotomo baby bottle green 5 ounces
Buying Options:
Amazon
Amazon
$13
See Now buybuyBaby
buybuyBaby
$24 for 2
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Target
$23 for 2
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Registry List:
Pros: Easy to clean, doesn't leak
Cons: More expensive than other brands, soft bottles may collapse while using

Why We
Love it
Community
Reviews
Why We Love It

Though not specifically made for preemies, these baby bottles were designed to mimic breastfeeding as closely as possible — ideal if you’re working on transitioning your preemie to breastfeeding. (It’s even round like a breast.) The texture of the bottle itself is also a plus for both mom and infant, since it’s soft, squishy and significantly more pliable than many other bottles. Vents help maintain a steady milk flow without excess air to cut back on gas. The wide-mouth design also makes these bottles easy to clean, happy parents say. “We bought both Dr Browns and ComoTomo and our LO far prefers the CT bottles. I’m thankful that’s her preference, because the bottles are so much easier to clean and they don’t leak!” says one WTE mom.

The 5-ounce bottles come with a slow-flow nipple, ideal for preemies getting the hang of feeding. When baby is ready, you can easily replace the nipples with medium- or fast-flow varieties — although note there are only three flow speed options, fewer than other brands on the market.

Material: BPA-free silicone

Capacity: 5 or 8 ounces

Bottles per Package: 1-6

Community Reviews

“We breast feed and only use Comotomo so far.”

- Cjh5ff

“My LO does much much better with the Comotomo. Less gagging, better latch onto the nipple. The latch is less shallow like on a normal nipple bottle. I recommend buying one.”

- silver0980

Most Affordable Preemie Bottle

Tommee Tippee Closer to Nature Bottles

tommee tippee closer to nature bottle set
Buying Options:
Amazon
Amazon
$25 for 4
See Now buybuyBaby
buybuyBaby
$24 for 3
See Now Target
Target
$13 for 3
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Registry List:
Pros: More affordable than other brands
Cons: Preemie-friendly nipples sold separately

Why We
Love it
Community
Reviews
Why We Love It

If you’re starting to see a trend here with anti-colic bottles, it’s for good reason. Tommee Tippee Closer to Nature Bottles are designed with a wide nipple base that’s meant to mimic mom’s breast to make the transition of going back and forth between bottle feeding and breastfeeding easier on baby. “We used Tommee Tippee and while we did wait a few weeks to introduce a bottle, they went back and forth with no problem,” says one WTE mom.

While the bottle is not specific to preemies, you can buy extra slow-flow nipples (sold separately) that might be better for preemies who still need to take things slow. At under $9 a bottle (or less, depending on the retailer), this is one of the cheaper options you’ll find on the market. 

Material: BPA-free plastic and silicone

Capacity: 5 or 9 ounces

Bottles per Package: 2, 3, 4 or 6 depending on retailer

Community Reviews

“I like Dr. Brown's preemie nipples but I also use Tommee Tippee because it is more like the shape of a breast.”

- LisaBrann

“We use tommee tippee bottles and dint have any problems with them. My son doesn't seem to struggle with the speed or flow of milk.”

- Melbmum2011

Best Preemie Bottle for Gassy Babies

NUK Simply Natural Bottle

nuk simply natural glass bottles
Buying Options:
Amazon
Amazon
$30 for 3
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Registry List:
Why We
Love it
Community
Reviews
Why We Love It

While some What to Expect parents say that feeding takes longer with these bottles than others, that's not a bad thing for preemies, since it can prevent gas from developing in baby's extra-small belly. The slow-flow nipple has multiple small openings, similar to a human nipple, to mimic breastfeeding, along with a vent to reduce gas and colic. The glass bottle is different from most preemie bottles on the market, which are typically plastic or silicone, but a nice option for parents who are wary of plastic. “My baby would only ever drink from nuk… and thank god because the pieces are easy to wash and manage,” adds one WTE mom.

Material: Glass and BPA-free silicone

Capacity: 4 or 8 ounces

Bottles per Package: 3

Community Reviews

“My baby 100% accepted Nuk and I would tell any breastfeeding mom to try it.”

- ForOnyx

“It’s the only type my LO likes.”

- Mlcxvc

Best Preemie Bottle for Colic

Nanobebe Flexy Silicone Baby Bottle

nanobebe flexy silicone bottle
Buying Options:
Amazon
Amazon
$18 for 2
See Now Target
Target
$19 for 2
See Now Walmart
Walmart
$25 for 3
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Registry List:
Pros: Parents say it helps with gas and spit up, easy to clean
Cons: Preemie nipple sold separately, not durable

Why We
Love it
Community
Reviews
Why We Love It

At first glance, you'll probably notice that this bottle doesn’t look much like the others — and that’s OK! The slanted design makes sense, given the natural positioning of how you feed your baby. The soft silicone exterior mimics the look and feel of a breast, while three vents work in unison to help remove air from baby’s bottle, preventing gas in the process. Non-collapsible ridges in the nipple help mimic a breastfeeding latch. The set comes with slow-flow nipples; you can buy nipples designed for preemies separately.

Material: BPA-free silicone

Capacity: 5 or 9 ounces

Bottles per Package: 2-3 depending on retailer

Community Reviews

“I had zero complaints about the bottle... easy to use, easy to clean, my baby took it well and could hold it just fine.”

- HollyStrong

“They've been great. Really easy to pump straight into and fridge or freeze. …Been really easy to go back and forth, so I can keep breastfeeding.”

- GraceRichards

American Academy of Pediatrics, Baby Bottles and Bisphenol A (BPA), February 2012.

American Academy of Pediatrics, Caring for a Premature Baby: What Parents Need to Know, October 2019. 

American Academy of Pediatrics, How Should I Feed My Premature Baby?, January 2023.

American Academy of Pediatrics, Practical Bottle Feeding Tips, December 2011.

American Academy of Pediatrics, Providing Breast Milk for Premature and Ill Newborns, May 2022.

Children’s Health Hospital, Tips for Feeding Premature Babies, Undated.

Centers for Disease Control and Prevention, Preterm Birth, November 2022.

UCSF Benioff Children’s Hospitals, Patient Education A-Z: Feeding Difficulties, Undated.

Anjuli Gans, M.D., Attending Physician, CHOP Karabots Pediatric Care Center, Philadelphia, Penn. 

Daniel S. Ganjian, M.D., Pediatrician, Providence Saint John’s Health Center, Santa Monica, Calif.